ABSTRACT
Background:Knee osteoarthritis (OA) damages the proprioceptors within the joint cavity which in turn may lead to impairment of balance, an integral part of mobility.Fears and beliefs about knee osteoarthritis in patients with knee osteoarthritis are found to have an adverse impact on their function. Objectives:The study aimed to evaluate the correlation between fearsand beliefs about knee osteoarthritis and balance in patientswith Knee OA. Material andMethods:In an observational analytical study males and females with OA knee were included. Fears and beliefs wereassesse d usingthe Knee Osteoarthritis Fears and Beliefs Questionnaire (KOFBeQ), balancewas tested using the Functional Reach Test (FRT) and pain was assessed by Visual Analogue Scale (VAS).Result:Forty-six patients were evaluated. Mean pain scorewas 4±1.5, FRT score 8.7±2.4inches, KOFBeq score33 ±13.8. Correlation was found using Spearman coefficient, r=0.178, p=0.23(balance and KOFBeq), r=-0.264, p=0.7 (pain and balance), r=-0.3, p=0.018(pain and KOFBeq) was seen.Conclusion:Fears and beliefs about knee osteoarthritis were present with impaired functional balance. Weaknegative correlationwas found between pain and balance and pain and fears and beliefs and no correlation were found between balance and fearsand beliefs.
ABSTRACT
Objective of the study: The present study was carried out to assess muscular fitness in healthy Indian school children between 9 to 12 years of age (older pediatric age-group) using Kraus-Weber Tests. The aim was to compare the results of this study with similar studies that have been carried out in India, Europe and America previously. Methods: Kraus-Weber Tests don’t require sophisticated equipment and are much easier to administer than traditional tools for analyzing muscular fitness like Electromyogram (EMG). Earlier studies have proven these tests to be excellent screening devices not only for physical but also psychosocial incompetence. They can actually be used as indicators of overall health in this older pediatric age-group. Results: The present study found more number of fitness and flexibility failures as compared to the last such study in India. In stark contradistinction to previous studies, girls have fared poorly than boys on the fitness front.Conclusion: These findings could be attributed to increased stress in school children especially in female students. A sharp dip has been observed in muscular fitness just prior to puberty (most probably due to hormonal causes).
ABSTRACT
An experiment was conducted in rabbits to evaluate the possible involvement of oxidative stress in iron-overload animals. Ten adult female New Zealand white rabbits were divided into 2 equal groups with 5 animals each. Group II animals received intramuscular iron dextran injections (120 mg/kg body wt/day) on alternate day for 14 days (8 injections), while Group I animals did not receive any iron supplementation to serve as negative controls. The blood samples were collected by cardiac puncture before the start of iron dosing and thereafter, at weekly intervals for 28 days. The samples were processed to measure blood iron concentration, packed cell volume, erythrocytic lipid peroxide (LPO) level, superoxide dismutase (SOD) and catalase (CAT) activities. The blood iron concentration showed a rising trend following repeated iron administration, and the mean level recorded on day 14 was significantly higher than respective day 0 value. LPO level remained significantly higher from day 14 onwards till the end of the observation period of 14 more days after cessation of iron adminstration. Erythrocytic superoxide dismutase activities showed a transient significant rise on day 7, and thereafter, showed a declining trend, but remained statistically comparable to respective day 0 or corresponding value of the control animals.
Subject(s)
Animals , Antioxidants/metabolism , Catalase/metabolism , Erythrocytes/metabolism , Female , Glutathione Peroxidase/metabolism , Iron/metabolism , Lipid Peroxidation , Lipid Peroxides/metabolism , Oxidative Stress , Rabbits , Superoxide Dismutase/metabolism , Time FactorsABSTRACT
The occurrence of cryptococcal meningitis in acute lymphoblastic leukemia (ALL), despite being immunosuppresed state is uncommon. We report a 28-year gentleman in the maintenance treatment phase of ALL developing cryptococcal meningitis. The diagnosis was made by positive India ink staining and detection of cryptola antigen by latex agglutination. The patient was successfully treated with amphotericin B. The rarity of this condition in ALL is briefly discussed.
Subject(s)
Adult , Amphotericin B/therapeutic use , Antifungal Agents/therapeutic use , Humans , Male , Meningitis, Cryptococcal/complications , Precursor Cell Lymphoblastic Leukemia-Lymphoma/complicationsABSTRACT
We report a case of ileal schwannoma who presented with bleeding per rectum. Three-vessel angiogram was the only diagnostic investigation, and revealed tumor blush in the mid-ileal region. On exploration, an intraluminal mass was found in the mid-ileal region along with a feeding vessel in the mesentery. Resection of the involved ileum with end-to-end anastomosis was done. Histopathology showed benign schwannoma of ileum involving the submucosa, muscularis propria and serosa.
Subject(s)
Aged , Angiography , Humans , Ileal Neoplasms/diagnosis , Male , Melena/etiology , Neurilemmoma/diagnosisABSTRACT
Helicobacter pylori infection of gastric antrum is associated with a majority of cases of peptic ulcer (70-100%). Studies have shown that when this organism is eradicated, the recurrence of ulcer falls to less than one-third of those in whom the infection persists or relapses. Monotherapy with bismuth salts, tinidazone or amoxycillin has been shown to result in early relapse and recurrence of ulcers. However, dual or triple therapy regimens are more effective. We conducted a randomised controlled study using tripotassium dicitrato bismuthate (TDB) (10 patients); amoxycillin (combined with ranitidine for ulcer healing) (9 patients) and dual therapy with both amoxycillin and TDB (10 patients). Our study showed that relapse rates at the end of 3 months was significantly less if dual therapy with TDB and amoxycillin is used as compared to TDB alone (p less than 0.05).
Subject(s)
Amoxicillin/administration & dosage , Anti-Ulcer Agents/administration & dosage , Drug Therapy, Combination , Follow-Up Studies , Helicobacter Infections/drug therapy , Helicobacter pylori , Humans , Organometallic Compounds/administration & dosage , Peptic Ulcer/drug therapy , Ranitidine/administration & dosage , RecurrenceABSTRACT
Helicobacter pylori is associated with 70-100% of peptic ulcers. Relapse of infection has been shown to cause recurrences of ulcers in a large number of studies. We diagnosed 137 cases of peptic ulcer (121 DU; 16 GU) during a 3 year period. Of these, 117 were positive for H pylori. Sixty six of the 117 cases staying in the vicinity of the Hospital were followed up for a minimum period of 3 months upto a maximum period of 3 years. In 91 examinations there was relapse of H pylori infection and ulcer recurrence was seen in 58 (63%), whereas ulcer recurred only in 6 out of 61 examinations where H pylori had not relapsed (10%). The difference was highly significant by Chi square test. (P less than 0.001).
Subject(s)
Adolescent , Adult , Female , Follow-Up Studies , Gastroscopy , Helicobacter Infections , Helicobacter pylori , Humans , Male , Middle Aged , Peptic Ulcer/microbiology , RecurrenceABSTRACT
Solasodine content in berries, leaves and stem of S. sisymbriifolium, using three different procedures, was 0.93, 0.73 and 0.23% respectively. Further in chromatogram not only solasodine but three more alkaloids (Rf 0.22, 0.48 and 0.88) were found which could not be identified due to lack of authentic samples.